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What is amutation?
The first thing which Mechanism of Mutation Assignment Help team wants students to know is about mutation. Mutation is the process of replication or recombination that brings about a permanent change in the DNA arrangement of nucleotides. Impaired DNA can be mutated either by replacement, deletion or addition of base pairs. Mutation is usuallyharmless excluding when they lead to cell death or tumor formation.
Types of Mutations:
According to Mechanism of Mutation Homework Help team, base knowledge is a must thingto gain a grip over some topic. Sothey preferred toimpart some light on the classification of mutations. They are as follows:
- Base Substitutions
- silent
- nonsense
- missense
- transversion
- transition
- Deletions
- Insertions
Causes of Mutations:
Mutation causes for the following reasons as mentioned below:
- Errors in DNA Replication
- Errors in DNA Recombination
- Chemical Damage to DNA
- Radiation
Consequences of Mutations:
Mutation occurs due to the following grounds:
- Silent mutation
- Missense mutation
- Nonsense mutation
Mechanism of mutation:
Mutations may be caused by external influences or unprompted cellular processes. The mechanism trails below.
Transformation of the methylated cytosine (methyl-cytosine) to thymine. We all know that a DNA molecule consists of four base pairs , uracil is one out of these four. As uracil is not a DNA portion, so mutation can be identified and fixed by base deletion. Take for instance, if DNA is similarto RNA, and consisted of uracil, then the cytosine to uracil mutation could be rectified only by divergence restoration. This may elucidate the reason of DNA choosing thymine, instead of uracil, in spite of uracil’s chemical structure being simpler than thymine. To know more on this topic click to myhomeworkhelp.com and opt for Mechanism of Mutation Assignment Help.
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